New Clinical Report Published

Primary Functions in Skincare:

  • Brightening agent Reduces hyperpigmentation and evens skin tone
  • Barrier booster Strengthens the skin’s natural protective layer
  • Anti inflammatoryCalms redness and soothes irritation
  • Sebum regulator Helps control oil production
  • Anti aging Improves fine lines, elasticity, and surface texture
  • Antioxidant Protects skin from oxidative stress

Scientific Validation:

  • Clinical studies support its efficacy at 2–5% concentrations for improving skin tone, reducing acne, and minimizing wrinkles
  • Recognized by dermatologists as a<bwell tolerated and versatile active for a wide range of skin types including sensitive and acne-prone skin
  • Studies published in the British Journal of Dermatology and Journal of Cosmetic Dermatology confirm measurable improvements in skin smoothness, elasticity, and reduced pigmentation with consistent use

Mechanism of Action:

  • Enhances ceramide production in the stratum corneum, improving moisture retention
  • Inhibits the transfer of melanosomes from melanocytes to keratinocytes, thereby reducing dark spots
  • Downregulates inflammatory markers in acne and rosacea
  • Improves NAD+/NADH ratio, essential for cellular repair and metabolism

Recommended Usage Level:

  • 1.5% typical usage in serums, moisturizers, and creams
  • Higher concentrations (up to 10%) used in targeted treatments with caution for sensitive skin

Stability & Compatibility:

  • Stable in water-based formulations at pH 5.7
  • Incompatible with low pH ingredients like pure L-ascorbic acid (Vitamin C) may cause flushing or reduce efficacy when combined incorrectly
  • Works synergistically with ingredients like zinc, hyaluronic acid, ceramides, and peptides

Synonyms:

  • Nicotinamide
  • Vitamin B3
  • 3-Pyridinecarboxamide

Skin Types:

  • Oily
  • Acne-prone
  • Hyperpigmented
  • Aging
  • Sensitive